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Innovative affinity-based system for blood
cell separation
Inovativni afinitetni sistem za ločevanje populacij krvnih celic
(ARRS: L4-1843)
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Project summary
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Title:
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Innovative
affinity-based system for blood cell separation
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Principal
Investigator:
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dr. Boris Gole
(Medical Faculty University of Maribor)
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Associated
research organizations:
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Faculty of Chemistry and Chemical Engineering,
University of Maribor
Strip's,
elektrotehnika - elektronika, d.o.o.
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Co-funding:
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Strip's,
elektrotehnika - elektronika, d.o.o.
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Associated from
Medical Faculty, University of Maribor:
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full prof. dr. Uroš Potočnik, assit.
prof. dr. Mario
Gorenjak, assit. prof. dr. Helena Sabina Čelešnik,
assist prof. dr. Katja
Repnik, Larisa Goričan, Gregor Jezernik,
assist. prof. dr. Uroš Maver, assist.
prof. dr. Tina
Maver, dr. Janja Stergar, Kristijan Skok, Lidija Gradišnik,
Tatjana Golob, Marko Milojević,
assist. prof. dr. Andraž Stožer,
full prof. dr.
Iztok
Takač
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Duration:
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1.7.2019
– 30.6.2022
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Iz
vsebine
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Short summary:
Currently,
systems offering high quality and realiable isolation of cells are
expansive and require a lot of hand-on work (FACS) or have low yield
and flow rates (MACS, etc.).
The
goal of this project is to create a novel, innovative cell isolation
system, which will enable easy and effective isolation of various cell
types from peripheral venous blood and umbilical cord blood with less
hands-on work, greater yield and lower cost than currently available
systems.
Role of Medical Faculty, University of Maribor:
Design
and preparation of cell isolation system, testing system on existing
cell cultures and biological samples (blood, umbilical cord blood,
providing biolocal samples for system testing and validation.
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Figure: Graphical
summary of the project.
Biologial
material (blood or umbilical cord blood) flows into the cell isolation
systen (patent application PCT/SI2018/050035 based on previous
project feasibility projections).
Undesired
cell types are discarded from the system while targeted cells are
separatelly removed.
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