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Innovative affinity-based system for blood cell separation

Inovativni afinitetni sistem za ločevanje populacij krvnih celic

(ARRS: L4-1843)

Project summary

Title:

Innovative affinity-based system for blood cell separation

Principal Investigator:

dr. Boris Gole (Medical Faculty University of Maribor)

Associated research organizations:

Faculty of Chemistry and Chemical Engineering, University of Maribor

Strip's, elektrotehnika - elektronika, d.o.o.

Co-funding:

Strip's, elektrotehnika - elektronika, d.o.o.

Associated from Medical Faculty, University of Maribor:

full prof. dr. Uroš Potočnik, assit. prof. dr. Mario Gorenjak, assit. prof. dr. Helena Sabina Čelešnik, assist prof. dr. Katja Repnik, Larisa Goričan, Gregor Jezernik,

assist. prof. dr. Uroš Maver, assist. prof. dr. Tina Maver, dr. Janja Stergar, Kristijan Skok, Lidija Gradišnik, Tatjana Golob, Marko Milojević,

assist. prof. dr. Andraž Stožer,

full prof. dr. Iztok Takač

Duration:

1.7.2019 – 30.6.2022

Iz vsebine

Short summary:

Currently, systems offering high quality and realiable isolation of cells are expansive and require a lot of hand-on work (FACS) or have low yield and flow rates (MACS, etc.). 

The goal of this project is to create a novel, innovative cell isolation system, which will enable easy and effective isolation of various cell types from peripheral venous blood and umbilical cord blood with less hands-on work, greater yield and lower cost than currently available systems.

 
Role of Medical Faculty, University of Maribor:

Design and preparation of cell isolation system, testing system on existing cell cultures and biological samples (blood, umbilical cord blood, providing biolocal samples for system testing and validation. 





Graphical summary of L4-1843 project

Figure: Graphical summary of the project.

Biologial material (blood or umbilical cord blood) flows into the cell isolation systen (patent application PCT/SI2018/050035 based on previous project feasibility projections).

Undesired cell types are discarded from the system while targeted cells are separatelly removed.